I am not able to send mail in roundcube.

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When i am tying to send mail in roundcube it gives an error as "SMTP Error (451): Failed to set sender (4.7.1 Service unavailable - try again later)." Please let me know if anyone has solution.
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johnpaulb-imhs1
Hello rohitk481993, Thank you for your question about sending errors in Roundcube. We are happy to help, but will need some additional information. Since you are not hosted with us, I cannot check your server logs. Have you checked the Mail logs for additional error messages? Have you contacted your host to see if they are aware of any server issues? If you have any further questions, feel free to post them below. Thank you, John-Paul